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Naproxen NSAIDs

(BRITISH) UK Trade name products: (Arthroxen) (Napratec) (Naprosyn) (Nycopren) (Pranoxen Continus) (Synflex)

(AMERICAN) US Trade name products which contain naproxen include: (Naprosyn) (Novonaprox) (Naproxen) (Naproxen Ds) (Apo-Napro-Na) (Apo-Naproxen) (Naprosyn-Sr) (Naxen) (Novonaprox Sodium) (Synflex)

INDICATION

A nonsteroidal anti-inflammatory agent used for the treatment of pain, fever, and inflammation.

SIDE EFFECTS

Decreased white blood cells, prolonged bleeding time, headache, sleepiness, dizziness, ringing in the ears, swelling, difficulty breathing, visual disturbances, GI distress, nausea, vomiting, ulcers, kidney disorders, elevated liver enzymes, rash, and itching.

INTERACTIONS and PRECAUTIONS

  1. Monitor closely when used with blood thinners (warfarin).
  2. Use with ACE inhibitors (captopril, enalapril, lisinopril) could reduce their effectiveness.
  3. Use with aspirin or alcohol can increase stomach ulcers or bleeding.
  4. Do not use with other nonsteroidal anti-inflammatories.
  5. Use with beta-blockers (propranolol, metoprolol, carteolol, labetalol) can decrease their antihypertensive effect.
  6. Use with cephalosporin class antibiotics can promote bleeding.
  7. Use with diuretics may decrease their diuretic effect.

USUAL DOSE

Adults: oral, 250, 375, or 500 mg two times a day; or extended-release tablets, 750 or 1,000 mg once a day in the morning or evening.

Paediatrics: 10 mg/kg body weight per day, given in two divided doses.

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