N.A.S.S Dingwall Branch Information Page

Paracetamol (UK), Acetaminophen (US)

INDICATION

An analgesic, antipyretic medication used for the control of mild pain and fever.

SIDE EFFECTS

Rash, hives, peripheral neuritis, and liver damage with toxic doses. Other side effects that are considered more rare include: hypersensitivity reactions and optic neuritis.

INTERACTIONS and PRECAUTIONS

1. Diflunisal increases blood levels of paracetamol or paracetamol.
2. Do not use this concurrently with (AZT) in the treatment of AIDS.
3. Frequent combined use with anticoagulants (Warfarin) may increase anticoagulant effect.
4. Chronic alcohol abuse with Paracetamol (paracetamol) use can increase the risk of liver toxicity.
5. Prolonged concurrent use of Paracetamol (paracetamol) with aspirin, other salicylates, or nonsteroidal anti-inflammatory agents can increase the risk of kidney toxicity.
6. Use with isoniazid may increase the risk of kidney and liver toxicity.

USUAL DOSE

Adults: 1-2 (325 mg tablets) every 4-6 hours. Extra-strength (500 mg) may be used 1-2 every 4-6 hours (no more than 4 gram/day).